Translatomics for eIF4A, differentiation and immunology

February 9th, 2025 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Saito et al. find that DMDA-PatA inhibits eIF4A activity through a mechanism distinct from similarly-acting eIF4a inhibitors. Miao et al. find […]

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Translatomics for CRC, lncRNA, m6A and circRNA

January 26th, 2025 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, we focus on the theme of colorectal cancer (CRC). Zhang et al. employed ribosome profiling to investigate the role of lncRNA-encoded

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Translatomics for HMPA, lncRNA and microprotein

February 2nd, 2025 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers: Xu et al. developed HMPA, which uncovers hidden peptides from noncoding regions using ribosome profiling and mass spectrometry, revealing roles in

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Hitting your target selectively. The potential of EIRNA Bio’s c-MAST Screening platform to rapidly identify off-target effects.

Hitting your target selectively. The potential of EIRNA Bio’s c-MAST Screening platform to rapidly identify off-target effects.

In the realm of drug discovery, understanding the mechanism of action of therapeutic compounds is crucial, and ribosome profiling (Ribo-seq) has emerged as a powerful tool for this purpose. Despite its strengths, the application of Ribo-seq in a high-throughput manner poses practical limitations. The resource-intensive nature of the technology makes it challenging to triage large

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Translatomics for microproteins, muscle and shape perception

January 19th, 2025 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers: Tzani et al. use ribosome profiling to highlight the significance of microproteins and non-canonical translation in CHO cells. Zhang et al.

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Translatomics for m6A, heat stress and mRNA decay

January 12th, 2025 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers: Yun et al. used ribo-seq and m6A-seq to uncover how novel duck reovirus induces translational shutoff in Muscovy ducklings by recruiting

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Translatomics for rice stripe virus, PEMV2 and Zika virus

January 5th, 2025 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Wang et al. identified the importance of analysing both transcriptional and translational landscapes to fully understand plant’s defence mechanism. Brown and May identified

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Translatomics for cell death, virus and autoimmunity

December 29th, 2024 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Gottlieb et al. identify a novel factor contributing to translational control of immune related genes in response to T cell activation,

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