
Ribosome Pausing: Mechanisms and Implications in Translation
Ribosome Pausing The process of translation is characterized by variation in the local decoding rates of specific mRNA codons. There are known cases where pausing or
Ribosome Pausing The process of translation is characterized by variation in the local decoding rates of specific mRNA codons. There are known cases where pausing or
Optimising Biotherapeutic Protein Yields The primary determinants for successful recombinant protein expression are high expression levels of the recombinant genes, translation efficacy and post-translational modifications.
Abiotic Stress Tolerance Translation is a tightly controlled mechanism in response to abiotic stress tolerance in plants, partly due to how energetically expensive this process
Biofuels and Commodities With the advent of genetic engineering, a revolution occurred within the sector of biofuel and commodity production. Suddenly, microbes were being utilised
Complete Differential Gene Expression Identifying what proteins are being expressed at a cellular level in response to a drug or as a consequence (or cause)
Viral-Host Interaction Translation within the context of viral-host interaction is a crucially important factor in determining the propagation of the invading pathogen. Due to their
Cancer Aetiology Translation is a key process in a wide range of cancers, being significantly altered to drive its initiation and progression. Practically all oncogenic
Cardiometabolic Health Cardiometabolic diseases, significant causal factors in heart attacks and strokes, are the leading cause of death worldwide. With the growing rates of cardiometabolic
Translatomics in Action: Neurological Disease The dysregulation of translation in the central nervous system (CNS) has been linked to multiple neurodegenerative diseases, making translatomics a
RAN-Translation in Neurological Disease A range of human neurological disorders occur due to nucleotide repeat expansions which can cause disease by protein gain-of-function, protein loss-of-function,