Translatomics in Action: Respiratory Illnesses Respiratory illnesses encompass a wide range of disorders affecting the lungs and other parts of the respiratory system. These illnesses
Melanoma Melanoma is a particularly aggressive cancer, well known for its ability to rapidly metastasize to other organs, making early diagnosis crucial. Alarmingly, it is
Translatomics, the comprehensive study of an organism’s translation processes, offers a profound understanding of how plants synthesize proteins and regulate gene expression in response to
The rapidly evolving field of cancer research has seen significant advances in understanding the complex mechanisms underpinning tumour development, progression, and resistance to therapy. Recent
Plant Immunity Plant immunity research has potential benefits in agriculture by reducing losses and increasing food security, as well as mitigating environmental impacts. Insights into
The Translatomics of SARS-CoV-2 Viruses, lacking their own cellular organelles, necessarily hijack its host’s translational machinery, namely the ribosome, to produce the proteins required for
Nonsense Suppression Therapy Nonsense mutations, single nucleotide changes which replaces a codon that encodes for an amino acid with a stop codon resulting in truncated
Small Molecules Targeting Translation In the present day, the vast majority of pharmaceutical therapeutics target specific proteins or enzymatic reactions. However, due to conformational challenges,
uORF detection Upstream open reading frames (uORFs) are sequences with start and stop codons found upstream of the main protein coding region in an area
Translation Elongation Rates In order to maintain a healthy proteome, the ribosome must not only generate sequences of peptides in sufficient quantities to serve their
