1. INTRODUCTION When delving into the realms of codon optimality, we must first take a step back to observe our definitions and origins. At the

Introduction In all forms of life, the ribosome is responsible for protein biosynthesis. In eukaryotes the 80S ribosome (70S in bacteria) is comprised of a

A Beginner’s Guide to Polyamines What are they? Polyamines are short organic molecules which have at least 2 amino (-NH2) groups. They are found in

Mini-Review: Ribosome Profiling Introduction TDP-43 is by far the most common factor associated with ALS, with aggregations of the protein being observed in in ~97%

Cell Specificity in Translation Transcription and translation are often thought to be coupled processes, with a rise in mRNA transcripts typically associated with an increase

Mini-Review: Alternative Proteoform Prediction It has been estimated that there are approximately 20,000 protein-coding genes in humans, however, when considering splice variants, the number of

Mini-Review: Ribosome Profiling Introduction Ribosome Profiling (Ribo-seq) is a deep-sequencing technique developed by Nicholas Ingolia and Jonathan Weissman that facilitates a genome-wide view of translation in