Introduction In all forms of life, the ribosome is responsible for protein biosynthesis. In eukaryotes the 80S ribosome (70S in bacteria) is comprised of a

A Beginner’s Guide to Polyamines What are they? Polyamines are short organic molecules which have at least 2 amino (-NH2) groups. They are found in

Mini-Review: Ribosome Profiling Introduction TDP-43 is by far the most common factor associated with ALS, with aggregations of the protein being observed in in ~97%

Cell Specificity in Translation Transcription and translation are often thought to be coupled processes, with a rise in mRNA transcripts typically associated with an increase

Mini-Review: Alternative Proteoform Prediction It has been estimated that there are approximately 20,000 protein-coding genes in humans, however, when considering splice variants, the number of

Mini-Review: Ribosome Profiling Introduction Ribosome Profiling (Ribo-seq) is a deep-sequencing technique developed by Nicholas Ingolia and Jonathan Weissman that facilitates a genome-wide view of translation in